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CLEVELAND — The Cleveland Guardians have called up top pitching prospect Gavin Williams to make his major league debut Wednesday against the Oakland Athletics, while starting pitcher Triston McKenzie will be shut down for up to six weeks — and possibly longer — with an elbow sprain that may yet require surgery.

Williams, 23, has risen quickly through the Guardians organization, and the club feels it’s time to see how his electric fastball plays against the game’s best players. A first-round draft pick in 2021, he is ranked No. 36 on ESPN insider Kiley McDaniel’s updated list of top 50 prospects.

The Guardians, who are two games behind first-place Minnesota in the AL Central, announced Williams’ start before opening a three-game series against the A’s.

Williams has gone 4-2 with a 2.39 ERA this season at Double-A Akron (three starts) and Triple-A Columbus (nine starts). He has 81 strikeouts in 60 innings. Last season, Williams struck out 149 in 115 innings.

McKenzie, 25, was placed on the 15-day injured list over the weekend with a strained ulnar collateral ligament. Guardians team physician Dr. Mark Schickendantz evaluated McKenzie at the Cleveland Clinic and advised he not throw for an extended period.

McKenzie, who missed the season’s first two months with a shoulder strain, will seek a second opinion with the team’s blessing. While he has long been viewed as a potential ace for Cleveland, McKenzie has also been slowed by injuries throughout his career.

“There may be a slightly different opinion than we have, we’ll see,” manager Terry Francona said Tuesday before the Guardians opened a three-game series against Oakland. “But that’s kind of where we are now. And when we have more information we will certainly share it.”

McKenzie’s injury is the latest for the defending AL Central champions, who are also without starter Cal Quantrill because of a shoulder strain.

Francona has been forced to use rookies Tanner Bibee and Logan Allen most of the season.

McKenzie made two starts before experiencing soreness in his elbow. He went 11-11 with a 2.96 ERA in 30 starts last season.

The Associated Press contributed to this report.

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Guardians’ Gavin Williams set for debut; Triston McKenzie shut down